By Air: : Chhatrapati Shivaji International Airport of Mumbai located about 25 kilometers from Thane via LBS Road and JVLR is the nearest air terminus from Thane. Being the second busiest airport in South Asia, and the largest and most important airport of the country, Mumbai Airport provides extremely good air connectivity with almost any part of the world. All the chief airports of India are linked with Chhatrapati Shivaji International Airport via air and almost each and every Indian Airline as well as a number of the foreign airlines cater their services here. To reach Thane from the airport you have several alternatives. The easiest and the most opted for preference is hiring a taxi that would reach you to Thane around in an hour. Local city buses (BEST, TMT and others) or the local trains are two other options to reach Thane from the Chhatrapati Shivaji International Airport.

By Rail: Thane Railway Station, the historical railhead of India that ushered the epoch of Indian Railway in the year 1853 lies on the Central Railway Line of Mumbai Suburban Rail Network. All the local trains, both slow and fast, that run on the central line between Chhatrapati Shivaji Terminus and Kasara, Kartjat and Khopoli stop at Thane. Moreover, the railway line that lies between Thane and Navi Mumbai connect Thane with Vashi, Nerul and Panvel.
Apart from the local trains of Mumbai Metropolitan, other major trains of Indian Railway that stop at Thane include, Deccan Express, Sinhagad Express, Mahalaxmi Express, Lokmanya TT Express, Konark Express, Sahyadri Express, Mumbai Mail, Koyna Express, Mumbai Chennai Express, Kamayani Express, Mahanagari Express, Nandigram Express, Jan Shatabdi Express, Vidarbha Express, Mumbai LTT Manmad Express, Intercity Express, Mangalore Express, Sewagram Express, Lashkar Express, Matsyagandha Express, Howrah Mail, Gorakhpur Express, Trivandram Express, Nagarcoil Express, Netravati Express, Tapovan Express, and many others.
Chief destinations of India accessible from Thane via train are: Mumbai, Pune, Nasik, Manmad, Nanded, Nagpur, Madgaon, Mangalore, Nagercoil, Trivandrum, Kanyakumari, Coimbatore, Chennai, Bhubaneshwar, Allahabad, Kolkata, Howrah, Guwahati, Varanasi, Rae Bareli, Gorakhpur, Agra, Gondia, Secunderabad, and so on.

By Road: Thane is linked with Mumbai as well as rest of the Maharashtra via a well established road network. Two of the most important roads of Mumbai namely LBS (Lal Bahadur Shastri Marg) and Eastern Express Highway connect the metropolitan with Thane. Both of these roads charge toll tax for entering Thane from Mumbai and vice versa. The famous toll gates and the well known landmarks of the city on these roads are Teen Hath Naka and Check Naka. Eastern Express Highway eventually turns into the Mumbai Agra NH – 3 and links Thane with Nasik, Dhule, Indore, Dewas, Gwalior, Agra and many other destinations on the way. Thane is connected with Pune via NH 4 and with Gujarat via NH 8. National Highway No 8 directly connects Thane with Ahmedabad in Gujarat. TMT (Thane Municipal Transport), NMMT (Navi Mumbai Municipal Transport), MBMT (Mira Bhayandar Municipal Transport), KDMT (Kalyan-Dombivli Municipal Transport), BEST and MSRTC connect Thane with other parts of Mumbai as well as Maharashtra via bus service. Thane is located about 34 km from CST, 145 km from Nasik, 146 km from Pune, 232 km from Ahmednagar, 271 km from Surat, 300 km from Dhule, 325 km from Aurangabad, 395 km from Vadodara, 514 km from Ahmedabad, 1170 km from Agra and 1377 km from Delhi.